A patch that can measure cortisol in sweat helps detect disease

Researchers have developed a prototype patch to measure cortisol, a stress hormone, in sweat that helps detect many diseases.

This patch can be stretched, placed directly on the skin, detects sweat and assesses how much cortisol a person produces. Stanford University scientists led by Alberto Salleo published this study in Science Advances.

Currently, patients need to spend several days waiting for results from the laboratory to determine whether their adrenal glands or pituitary are functioning properly.

This patch can be stretched, placed directly on the skin.

Dr. Onur Parlak, a postdoctoral researcher at the Salleo lab, said: “We are particularly interested in sweat, because it provides non-invasive and continuous monitoring of biomarkers. Different for a variety of physiological states. The results of this study provide a new method for early detection of various diseases and evaluation of sports performance “.

Researchers note that people with an imbalance can monitor their status.

They said: “Biosensors can be worn to replace the hospital-focused health care system with home-made diagnostics to reduce health care costs and diagnosis time. Guess by providing real-time, non-invasive analysis.

One challenge in developing a sensor for sweat is that cortisol does not have a positive or negative charge.

Scientists have built a rectangular sensor around a membrane that only binds to cortisol and absorbs sweat through holes at the bottom of the patch. Sweat is concentrated in a reservoir and it is covered with a sensitive membrane with cortisol. A waterproof layer protects the patch from contamination ..

Parlak checked the device on two volunteers who ran for 20 minutes with patches on their arms. In laboratory and real-world tests the results are similar. The sticker is connected to the device for analysis. Researchers want to develop the patch into a fully integrated and reusable system.

Your first memory is only fiction

According to research from Lon Don City University, the earliest memories of people come from the age of 3, contrary to popular belief that the human brain can create memories earlier.

A new report, published by a research facility in the Clerkenwell area of ​​London, found that any memory from 2 years and a half is likely to be “fiction.”

This is true even with four out of ten people (40%) claiming that they have clear memories from their early years.

But according to Pastest, which provides medical research review materials, memories are much more complicated than the way people understand them.

The memories are much more complicated than the way people understand them.

They say that memories are not stored in the brain like books in a library, but like a jigsaw puzzle, in which different parts of the brain put together to form a whole body.

Dr. Shazia Akhtar, the first author on the new research paper, described the original fictional memories in our lives as a “mental symbol like a sentimental memory”.

He added that these memories include: “memory pieces of initial experiences and some facts or information about their own childhood”.

Simply put, information about your early years from things like photos, conversations or things around you as you grow up becomes the center of your original “memories.”

These memories are put together by appropriate guesswork about age.

The co-author reports, Professor Martin Conway asserts that people cannot know that their earliest memories are fictitious because of the complex nature of the brain.

He said: “Over time, these pieces will gradually become a memory and they will often start adding other things like a series of toys until complete. Importantly, people who remember these memories do not know it is fiction. In fact, when people are told that their memories are false, they often don’t believe it. This is partly due to the fact that systems allow us to remember things very complicated. It is not until we are about five or six years that we form memories like adults developed by the brain and by our mature awareness of the world. ”

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